Bone Marrow Transplant

Bone Marrow Transplant

Bone Marrow Transplant

Bone Marrow Transplant is a procedure to replace damaged or destroyed bone marrow with healthy bone marrow stem cells.Bone marrow is the soft, fatty tissue inside your bones. The bone marrow produces blood cells. Stem cells are immature cells in the bone marrow that give rise to all of your different blood cells.

There are 3 kinds of bone marrow transplants:

1. Autologous Bone Marrow Transplant: The term auto means self. Stem cells are removed from you before you receive high-dose chemotherapy or radiation treatment. The stem cells are stored in a freezer. After high-dose chemotherapy or radiation treatments, your stems cells are put back in your body to make normal blood cells. This is called a rescue transplant.

2. Allogeneic Bone Marrow Transplant:
The term also means other. Stem cells are removed from another person, called a donor. Most times, the donor’s genes must at least partly match your genes. Special tests are done to see if a donor is a good match for you. A brother or sister is most likely to be a good match. Sometimes parents, children, and other relatives are good matches. Donors who are not related to you, yet still match, may be found through national bone marrow registries.

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3. Haploidentical Bone Marrow Transplant:
This is a type of allogeneic transplant. An HLA-haploidentical donor shares a haplotype with the transplant recipient. This means that the donor and recipient have the same set of closely linked HLA genes on one of the two Number 6 chromosomes they inherited from their parents. Rather than being a perfect match for each other, they are a half-match.

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